Project Code
MRCNMH25Ba Fairchild
Research Theme
Neuroscience and Mental Health
Project Summary Download
Summary
Childhood maltreatment is a major risk factor for Conduct Disorder (CD), a condition characterized by antisocial and aggressive behaviours. The ‘ecophenotype hypothesis’ suggests that maltreatment-related CD differs from non-maltreatment-related CD in severity, developmental course, treatment response, and neurobiological mechanisms. This PhD project aims to explore these differences using various large-scale datasets, including data from the recently-established ENIGMA-Antisocial Behavior Working Group (https://enigma.ini.usc.edu/ongoing/enigma-antisocial-behavior/). The research will compare maltreated and non-maltreated youth with CD in clinical profiles, developmental trajectories, brain structure and connectivity. The findings could inform the development of diagnostic criteria (DSM/ICD) and lead to personalized treatments for maltreated youth with CD.
Lead Supervisor
Dr Graeme Fairchild
Lead Supervisor Email
gf353@bath.ac.uk
University Affiliation
Bath