Project Code
MRCNMH25Br Chrobok
Research Theme
Cross-Cutting
Infection, Immunity, Antimicrobial Resistance and Repair
Neuroscience and Mental Health
Population Health Sciences
Project Summary Download
Summary
Most physiological processes including feeding follow circadian (~24h) cycles. In mammals, these rhythms are generated by endogenous ‘body clocks’ within the brain. Dysfunction of these body clocks can contribute to obesity and other metabolic disorders. Our studies focus on a site in the brainstem that controls appetite which we have discovered also has robust circadian timekeeping. This project aims to understand how cannabinoids, substances known to promote appetite, impact cell-cell communication and the timing of food intake via the activity of this brainstem satiety centre.
Lead Supervisor
Dr Lukasz Chrobok
Lead Supervisor Email
lukasz.chrobok@bristol.ac.uk
University Affiliation
Bristol