Project Code MRCIIAR26Br Dowsey Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Fungal infections have become a major and growing global health crisis, causing an estimated 3.8 million deaths each year particularly…
Microplastics, big problems: dissecting effects on the immune system and skeletal repair
Project Code MRCIIAR26Br Hammond Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary There is a growing awareness that micro- and nanoplastics, which are increasingly prevalent in our environment, pose risks to human…
Bridging the Gap: Improving Access to Care for people at Risk of Type 1 Diabetes
Project Code MRCIIAR26Br Long Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary A paradigm shift is underway in type 1 diabetes (T1D) treatment. For over a century, T1D has been managed, but…
Hidden codes: Genetic Determinants of HIV-1 Fitness and Immune Recognition
Project Code MRCIIAR26Br Mann Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This project addresses the ongoing challenge posed by HIV-1, a virus infecting approximately 38 million people globally, with Subtype C…
Exploring Communication Networks in DNA Gyrase: A Pathway to Next-Generation Antibiotic Discovery
Project Code MRCIIAR26Br Oliveira Project Type This is a computational led project using biomolecular simulations, but will include laboratory experiments to test/validate predictions arising from the simulations. Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Bacterial…
Elucidating genetic and immune signatures of severe dengue
Project Code MRCIIAR26Br Rivino Project Type This project is cross-disciplinary and includes both wet and dry lab work (approx 60% wet lab and 40% dry lab). Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Dengue is…
Targeting Antioxidant Metabolic Pathways in HTLV-1 Associated Adult T-Cell Leukemia
Project Code MRCIIAR26Br Shytaj Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Human T-lymphotropic virus 1 (HTLV-1) causes lifelong infections and can lead to severe diseases like adult T-cell leukaemia/lymphoma (ATL), with…
Overcoming β-lactamase-mediated antibiotic resistance by combining biomolecular simulation and experiment
Project Code MRCIIAR26Br Van der Kamp Project Type The project will be a combination of dry and wet; with a focus on dry-lab (computational) activities, but wet-lab based activities are also a key component (enzyme production & purification, enzyme kinetics,…
Systematic investigation of the interaction of human cytomegalovirus with the immune system
Project Code MRCIIAR26Ca Fielding Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Human cytomegalovirus (HCMV) is a herpesvirus that causes significant disease in individuals with impaired immune control. HCMV causes significant morbidity…
Understanding the dual roles of Wnt signalling in kidney injury, inflammation and repair following acute kidney injury
Project Code MRCIIAR26Ca Fraser Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary How does Wnt signalling determine tissue repair versus scarring following Acute Kidney Injury (AKI)? AKI is very common. Some people…