Brain growth mechanisms involving axon volume and myelination linked with autism spectrum disorder.

Project Code

MRCNMH25Ba Ward

Research Theme

Neuroscience and Mental Health

Project Summary Download

Summary

Correct axonal volume and myelination are essential for neuronal function. Little is currently known about mechanisms controlling axon volume and loss of brain myelin occurs in ageing and common age-related neurodegenerative conditions such as Alzheimer’s disease. Growing evidence also links altered myelin levels with autism spectrum disorder (ASD; affecting some 1 in 160 people worldwide).  The project aims to establish the mechanisms of action for a novel regulator of axon volume and myelination that is proposed to form a link with ASD.

Lead Supervisor

Professor Andrew Ward

Lead Supervisor Email

bssaw@bath.ac.uk

University Affiliation

Bath