Characterising the role of inflammation in the development of multiple myeloma

Project Code

MRCPHS25Br Goudswaard

Research Theme

Population Health Sciences

Project Summary Download

Summary

Multiple myeloma (MM) is an incurable blood cancer, caused by the proliferation of plasma cells in the bone marrow. The link between chronic inflammation and the development of MM requires further investigation. This multidisciplinary project aims to (1) use samples from a national MM screening programme in Iceland to identify inflammatory proteins that may be involved in MM development, (2) use causal inference approaches to determine modifiable risk factors which may affect levels of inflammatory proteins, (3) characterise the effect of implicated inflammatory proteins on cell growth and proliferation in vitro. 

Lead Supervisor

Dr Lucy Goudswaard

Lead Supervisor Email

lucy.goudswaard@bristol.ac.uk

University Affiliation

Bristol