Project Code
MRCNMH25Ex Piers
Research Theme
Neuroscience & Mental Health
Project Summary Download
Summary
Using induced pluripotent stem cells, we can generate complex multi-cellular 3D human brain tissue models in a dish, termed cerebral organoids. These models provide unique opportunities to study human-centric biological questions about brain function. However, the use of such models is confounded by variability, poor long-term viability, and a limited diversity of cell types. This project will take a multi-disciplinary approach, incorporating 3D bioprinting and novel cell culture techniques to allow us to generate highly reproducible organoids that can be used to study neuronal function in health and disease.
Lead Supervisor
Dr Thomas Piers
Lead Supervisor Email
t.piers@exeter.ac.uk
University Affiliation
Exeter