Finding the missing link in memory networks: Deciphering cortical-thalamic communication pathways critical for successful memory

Project Code

MRCNMH25Br Warburton

Research Theme

Neuroscience & Mental Health

Project Summary Download

Summary


Our memories are stored in networks across the brain.   Two regions, the lateral entorhinal cortex (LEC) and nucleus reuniens (NRe) are key parts of such a network, and pathology in these regions causes memory loss in old age and in  brain disorders, such as dementia and schizophrenia.  LEC and NRe are strongly interconnected, but we don’t know how they communicate during memory processing.  To answer this question  the project will use a range of cutting-edge behavioural, optical and electrophysiological techniques to explore when and how information is relayed between the cortex and thalamus  to enable us to learn and remember.

Lead Supervisor

Professor Clea Warburton

Lead Supervisor Email

e.c.warburton@bristol.ac.uk

University Affiliation

Bristol