Project Code
MRCNMH25Br Robinson
Research Theme
Neuroscience & Mental Health
Project Summary Download
Summary
Apathy is a debilitating and highly prevalent symptom in people with Parkinson’s disease. It is often refractory to conventional dopaminergic therapy and is associated with poorer health-related quality of life. No specific treatment for apathy exists, partly as little is known about its neurobiology. This project aims to investigate the neurobiology of apathy and explore the mechanisms of potential therapeutics using a combination of behavioural studies, pharmacology and targeted manipulations of underlying circuits implicated in motivated behaviours. The project will also be supported by clinical colleagues currently involved in clinical trials in Parkinson’s disease.
Lead Supervisor
Professor Emma Robinson
Lead Supervisor Email
pmesjr@bristol.ac.uk
University Affiliation
Bristol