Project Code
MRCIIAR25Br Van Der Kamp
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
Antibiotic resistance threatens human health. β-lactamases cause resistance to β-lactams, the most widely used antibiotics. Class C β-lactamases are not well understood, but variants are emerging that help bacteria evade even ‘last resort’ treatments. Combining computer simulation and experimental methods can explain how, guiding us to regain the upper hand in the ‘biochemical warfare’ between humans and bacteria.
Lead Supervisor
Dr Marc Van der Kamp
Lead Supervisor Email
marc.vanderkamp@bristol.ac.uk
University Affiliation
Bristol