Project Code MRCNMH25Ba Lancaster Research Theme Neuroscience and Mental Health Project Summary Download Summary Severe mental illness with psychosis symptoms (e.g. bipolar disorder, schizophrenia) are reliably linked to alterations in brain reward circuitry. Neuroimaging techniques can predict diagnosis of individuals…
Man up? Examining attitudes and experiences around mental health and help-seeking
Project Code MRCNMH25Ba Lambert Research Theme Neuroscience and Mental Health Project Summary Download Summary “Women seek help – men die”. Comparatively lower rates of mental illness among men than women are not explained by better health among men. Men face…
Understanding the impact of childhood maltreatment on brain structure and connectivity in Conduct Disorder
Project Code MRCNMH25Ba Fairchild Research Theme Neuroscience and Mental Health Project Summary Download Summary Childhood maltreatment is a major risk factor for Conduct Disorder (CD), a condition characterized by antisocial and aggressive behaviours. The ‘ecophenotype hypothesis’ suggests that maltreatment-related CD…
Can young people’s cognitive style explain associations between social media use and mental health?
Project Code MRCNMH25Ba Button Research Theme Neuroscience and Mental Health Project Summary Download Summary In public discourse, social media is often claimed to be bad for young people’s mental health. This simple view is not supported by science, where the…
Brain stimulation and neurophysiological investigations of central nervous system changes in pathological pain, and their augmentation by treatment.
Project Code MRCNMH25Ba Bultitude Research Theme Neuroscience and Mental Health Project Summary Download Summary Chronic pain can involve changes throughout the central nervous system (CNS). Some treatments aim to alter CNS function, with limited results. This could be because research…
Synthetic heroin: understanding the dangers of nitazene drugs
Project Code MRCNMH25Ba Bailey Research Theme Neuroscience and Mental Health Project Summary Download Summary “Drug-related deaths are now at the highest ever recorded in the UK, the majority involving opioid drugs. Recently, a new class of synthetic opioids known as…
Airborne transmission of pathogens: defining microbial and environmental factors affecting survival in aerosols.
Project Code MRCIIAR25Ba Preston Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Numerous bacteria transmit between hosts via the air, representing a key step in the pathogen lifecycle. However, we know little about the microbial and…
Tackling Antimicrobial Resistance with Targeted Covalent Macrocycles
Project Code MRCIIAR25Ba Lovell Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Infections with drug-resistant bacteria are major threats to human health. Discovering novel druggable targets for antimicrobial development is a pivotal task to guarantee effective…
Using AI to understand defence and counter-defence systems between bacteria and phage
Project Code MRCIIAR25Ba Iqbal Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Bacteria have been engaged in a war with the viruses that predate on them (“phage”) for millions of years, both sides developing defence/counter-defence systems.…
Environmental and genetic determinants of transmission by a parasitic nematode
Project Code MRCIIAR25Ba Hunt Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary The parasitic nematode Strongyloides infects >600 million people and is transmitted between hosts through a larval stage in the soil. We know little about…