Decoding HIV-1: Genetic Influences on Virus Replication and Transmission

Project Code MRCIIAR25Br Mann  Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This project addresses the ongoing challenge posed by HIV-1, a virus infecting approximately 38 million people globally, with Subtype C (C-HIV) as the most…

Developing new weapons to fight drug-resistant superbugs – targeting lipoteichoic acid biosynthesis

Project Code MRCIIAR25Br Laabei Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antimicrobial resistance (AMR) has been described as the silent pandemic, fuelled in part by insufficient antibiotic development. We have identified novel small molecules that…

Emerging co-resistance to first and second line antibiotics in urinary pathogens and implications for the control of urosepsis.

Project Code MRCIIAR25Br Avison  Research Theme Infection, Immunity, Antimicrobial Resistance and Repai Project Summary Download Summary Reducing antibiotic resistance (ABR) among urosepsis pathogens – derived from urinary tract infection (UTI) via pyelonephritis – is central to the UKs ABR-reduction strategy.…