Research in our Infection, Immunity and Antimicrobial Resistance (IIAR) theme aims to improve human health by advancing understanding of infectious disease, the role of the immune system in inflammation, immune-mediated disease and cancer, and antimicrobial resistance at the pathogen level. Findings may contribute to improved diagnosis, disease prevention, and stratification of treatment.
While closely connected the theme comprises three distinct areas:
Infection
Studies to enhance understanding of the pathogenesis and host–pathogen interactions of infectious agents by investigating mechanisms of transmission, colonisation and invasion; host susceptibility and immune evasion strategies; and factors driving disease severity and outcomes.
Immunity
Studies to enhanceunderstanding of the causes and mechanisms of immune pathology or immune dysfunction across a range of areas including inflammation, allergy, transplantation, systemic immune disorders, autoimmune disease, and immune oncology.
Antimicrobial Resistance
Studies to enhance detection, inform prevention and control, and support the development of strategies to mitigate or overcome resistance by investigating the molecular mechanisms and selective pressures that drive the emergence, evolution, and transmission of resistance in pathogens.
