Project Code MRCIIAR26Ca Parmeggiani Project Type The project combines dry- and wet-lab elements but aligns more closely with a wet-lab based project considering the costs needed to deliver the work. Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary…
Identification of novel antifungals: Synthesis, structure-activity correlation, and antifungal activity of novel molecular scaffolds from repurposable drugs
Project Code MRCIIAR26Ca Pertusati Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Fungal infections are a major threat to public health as they are becoming increasingly resistant to treatment. Only four classes…
Can Damage Associated Molecular Patterns be targeted to reduce susceptibility to infections in people with Chronic Kidney Disease?
Project Code MRCIIAR26Ca Raby Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary People with chronic kidney disease (CKD) are more vulnerable to infections, in part because their immune systems don’t function properly.…
Stop “Superbugs” to fight antimicrobial resistance
Project Code MRCIIAR26Ca Serpi Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary While antibiotics have revolutionised the landscape of medicine saving millions of lives, their misuse has also resulted in the rise…
From Survivor Blood to Curing Cancer
Project Code MRCIIAR26Ca Sewell Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary How do rare patients cure their own cancer?Some individuals with advanced cancers achieve complete remission, defying the odds without standard…
Immunological determinants of human cytomegalovirus control
Project Code MRCIIAR26Ca Stanton Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Lead Supervisor Professor Richard Stanton Lead Supervisor Email StantonRJ@cardiff.ac.uk University Affiliation Cardiff
Determining the potential human health impacts of microplastic contamination via direct injection, a novel exposure route for MP from medicinal products
Project Code MRCIIAR26Ex Ball Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Environmental microplastics are a human health concern. Ingestion/inhalation have been thought to be the predominant routes into the human body,…
Decoding Lupus: using liquid biopsies to understand autoimmunity
Project Code MRCIIAR26Ex Cano-Gamez Project Type Mixed (50% wet lab, 50% dry lab) Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Lupus is a serious autoimmune disease where the immune system attacks the body’s own cells.…
Developing antibiotic potentiators against highly antibiotic resistant human pathogens using the model organism Galleria Mellonella
Project Code MRCIIAR26Ex Harmer Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antimicrobial resistance is an increasing societal issue, contributing to ~5,000,000 deaths in 2019. The highest priority bacterial pathogens account for…
Uncovering new genetic mechanisms of beta-cell autoimmunity to better understand type 1 diabetes
Project Code MRCIIAR26Ex Johnson Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This project uses a unique collection of samples from people with diabetes to address a fundamental question: What are the…