Neural Mechanisms of Pain Relief: Comparing Cognitive Training and Neurostimulation Interventions

Project Code MRCNMH26Ba Khatibi Project Type Wet and dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Neuropathic pain (like diabetic-related peripheral neuropathy) is a persistent condition where the source of the pain isn’t tissue injury. Instead,…

Investigating how addiction to vaping compares to addiction to smoking

Project Code MRCNMH26Ba Khouja Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Vaping is less harmful than smoking and can help people stop smoking, but many people report feeling more addicted to vaping, describing…

Tackling Alzheimer’s with Smart Protein Removal Tools

Project Code MRCNMH26Ba Licchesi Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Targeted Protein Degradation (TPD) is a new approach that helps cells remove harmful proteins linked to diseases like Alzheimer’s. It uses special…

Selective Dephosphorylation of α-Synuclein in Parkinson’s Using PhosTAC Peptides

Project Code MRCNMH26Ba Mason Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Phosphorylation of the protein α-synuclein at serine 129 (pS129) is a defining feature of Parkinson’s disease and related conditions. This project will…

RNA-dependent regulation of the KAP1 chromatin protein controls neuronal stem cell function

Project Code MRCNMH26Ba Vance Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary The mammalian genome encodes hundreds of RNA binding proteins that associate with RNA using poorly defined modes of action. Mutations in these…

Bio-Computational Approaches to Understanding Transition to Psychosis

Project Code MRCNMH26Ba Walton Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This project aims to advance our understanding of psychosis by identifying the biological mechanisms that underlie its diverse symptom profiles. Moving beyond…

The Experience and Impact of Psychedelic Therapy as Treatment for Mental Health Disorders in Women Survivors of Sexual Assault

Project Code MRCNMH26Ba Williamson Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Sexual assault (SA) often leads to mental health difficulties and, as standard treatments have poor response rates, many survivors suffer with long-term…

Transforming Obesity Care in Idiopathic Intracranial Hypertension: A Person-Centred, Multidisciplinary Approach

Project Code MRCNMH26Br Atan Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Idiopathic intracranial hypertension (IIH) is a serious neurological condition linked to obesity—but weight loss isn’t simple when disordered eating, trauma, and mental…

Can experiences in Virtual Reality change body perception and satisfaction, in people with and without eating disorders?

Project Code MRCNMH26Br Bould Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Current treatments for eating disorders only work for around two thirds of those affected, so it is vital to develop novel treatments.…

Understanding Combination Use of Tobacco, E-cigarettes, and Cannabis: Predicting Modifiable Risks and Treatment Pathways Using Machine Learning

Project Code MRCNMH26Br Burke Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Combination use of tobacco, e-cigarettes, and cannabis is increasingly common, particularly among young people, yet little is known about how these patterns…