Quietly healing trauma: enhancing emotional processing during sleep with targeted memory reactivation

Project Code MRCNMH26Br Purple Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Why do some people recover from trauma while others develop post-traumatic stress disorder (PTSD)? Sleep is known to play an essential role…

Using genetics to understand neurodevelopmental outcomes in children born with cleft from a clinical birth cohort

Project Code MRCNMH26Br Stergiakouli Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This project will provide in-depth training in genetic epidemiology, neurodevelopmental disorders, cohort studies and cleft. The student will have the opportunity to…

Unlocking the causes of eating disorders: investigating risk factors across development

Project Code MRCNMH25Ca Chawner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Tackling eating disorders is of growing importance in society, with increasing numbers of children and young people referred to eating disorder services.…

A High-Efficiency and Sustainable Next-Generation Nanotherapeutic platform to Improve Astrocytoma Outcomes

Project Code MRCNMH26Ca Duc Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary In 2023, the Welsh and UK Government emphasised the urgent need for astrategic plan prioritising research in brain tumour therapy. Astrocytoma,comprising 1/3…

How ADHD affects curiosity and curiosity-based learning

Project Code MRCNMH26Ca Gruber Project Type The project will combine behavioural and neuroimaging studies (in particular, functional Magnetic Resonance Imaging, fMRI) in human participants. Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project explores how curiosity…

SONIC-Glaucoma: Stimulation Of Neuroprotective & Immunomodulatory Cargos via Ultrasound in Glaucoma

Project Code MRCNMH26Ca Mead Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Glaucoma causes progressive retinal ganglion cell (RGC) loss and remains without effective neuroprotective therapy. While platelet-derived growth factor (PDGF) and brain-derived neurotrophic…

Investigating Neurodevelopmental Disorders Through the Lens of UPF3B Syndrome

Project Code MRCNMH26Ca Ngo Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Neurodevelopmental disorders (NDDs) like autism and ADHD affect millions, yet the underlying causes remain unclear. This PhD project investigates how mutations in…

Novel area-modulation stimuli for identifying changes in visual field sensitivity in Age-related Macular Degeneration (AMD)

Project Code MRCNMH26Ca Redmond Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Age-related macular degeneration (AMD) is one of the world’s leading causes of sight loss. Traditional measures of vision in AMD are of…

When DNA Breaks and Mitochondria Fail: Investigating Drivers of Huntington’s Disease

Project Code MRCNMH26Ca Smith Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Huntington’s disease (HD) is a fatal inherited brain disorder with no effective treatment. It causes specific neurons in the brain to degenerate,…

Pain as neurobiological surprise: Using human brain imaging and animal studies to advance new concepts in persistent pain.

Project Code MRCNMH26Ca Tackley Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Complex nervous systems attempt to minimise surprise and aid survival by forming predictions about the world. Surprise signals danger: it is evidence…