Project Code MRCNMH26Br Atan Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Idiopathic intracranial hypertension (IIH) is a serious neurological condition linked to obesity—but weight loss isn’t simple when disordered eating, trauma, and mental…
Can experiences in Virtual Reality change body perception and satisfaction, in people with and without eating disorders?
Project Code MRCNMH26Br Bould Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Current treatments for eating disorders only work for around two thirds of those affected, so it is vital to develop novel treatments.…
Understanding Combination Use of Tobacco, E-cigarettes, and Cannabis: Predicting Modifiable Risks and Treatment Pathways Using Machine Learning
Project Code MRCNMH26Br Burke Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Combination use of tobacco, e-cigarettes, and cannabis is increasingly common, particularly among young people, yet little is known about how these patterns…
Chrono-nutrition and Chrono-pharmacology: Investigating the Impact of Intermittent Fasting and Timed Pharmacological Treatments for Obesity Management
Project Code MRCNMH26Br Chrobok Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Most physiological processes, including feeding, follow circadian (~24h) cycles. In mammals, these rhythms are generated by endogenous ‘body clocks’ within the brain.…
Alternative mitochondrial destinations of PINK1 and its role in Parkinson’s Disease
Project Code MRCNMH26Br Collinson Project Type It is both a wet and a dry project. Research Theme Neuroscience and Mental Health Project Summary Download Summary Mitochondria are vital for energy production, cell function and homeostasis, and thereby health. This project…
Unlocking the secrets of fentanyl: exploring the anomalous pharmacology of fentanyl at the μ-opioid receptor
Project Code MRCNMH26Br Corey Project Type The project will be chiefly a dry project, but with the opportunity to work in the labs of the co-supervisors. It will be partly down to the student how much they do, however they…
Understanding and reprogramming axonal transport with protein design
Project Code MRCNMH26Br Cross Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Intracellular transport is essential for organising and maintaining the function of eukaryotic cells. This is particularly important in neurons, where cargo must…
Targeting lysosomal dysfunction to treat age-related macular degeneration
Project Code MRCNMH26Br Dick Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Projected to affect 288M by 2040, there are…
Towards a better understanding and treatments for the rare genetic brain disorder called CASK
Project Code MRCNMH26Br Hodge Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary CASK is a synaptic scaffolding molecule and kinase with mutations causing brain and behavioural defects including severe learning difficulties, movement and sleep…
The impact of parental mental health on the brain bases of early executive function development
Project Code MRCNMH26Br Holmboe Project Type The project is lab based and involves cognitive testing and neuroimaging of young children. Research Theme Neuroscience and Mental Health Project Summary Download Summary In recent years we have made new discoveries in how…