Project Code MRCPHS26Br Sanderson Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary Cardiovascular disease is a major cause of ill health in later life. However, development of this disease is likely to be influenced by…
Disrupted Mechanical Signalling at the Golgi apparatus as a Driver of Osteoarthritis Progression
Project Code MRCPHS26Br Stevenson Project Type Wet lab Research Theme Population Health Science Project Summary Download Summary Nearly 8% of the global population is living with osteoarthritis. The mechanisms of disease are poorly understood, however a major risk factor is…
What are the biological mechanisms underlying the association between smoking, smoking cessation and mental health: a triangulation approach
Project Code MRCPHS26Br Taylor G Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary What are the biological mechanisms underlying the association between smoking, smoking cessation, and mental health? A growing body of evidence supports smoking…
Modelling and Communicating Avian Influenza Spillover at the Human–Wild Bird Interface: A One Health Approach
Project Code MRCPHS26Br Thomas Project Type Dry and wet lab, including field work. This is an interdisciplinary project.Predominantly the student will be dry lab to conduct modelling and co-production aspects. The student can participate in data collection in the field,…
Mental health of young people with a disability or chronic illness: a focus on intersectional inequalities
Project Code MRCPHS26Br Tinner Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary Mental health outcomes are socially patterned, differing by gender, race and ethnicity, disability, and socio-economic status (SES). A gap remains regarding intersectional inequalities…
Modelling the health harms of homelessness and other social exclusions, and impact of interventions to mitigate their effects
Project Code MRCPHS26Br Vickerman Project Type Dry lab Research Theme Population Health Science Project Summary Download Summary Homelessness is an increasing problem which is associated with considerable morbidity and mortality in the UK. Homelessness is also associated with other forms…
Investigating the role of the microbiome in obesity-driven colorectal cancer development
Project Code MRCPHS25Br Wade Research Theme Population Health Sciences Project Summary Download Summary Alarmingly, the incidence of early-onset colorectal cancer (EOCRC) is increasing rapidly in the UK. This rise may be, in part, attributable to obesity but exactly how obesity…
Metabolomic characterisation of adiposity across the life course
Project Code MRCPHS25Br Timpson Research Theme Population Health Sciences Project Summary Download Summary Adiposity, measured by body mass index (BMI), is linked to a range of health outcomes, but the underpinning biology is less understood. Metabolomics (the large-scale study of…
Using genetics to understand mental health outcomes in children from a clinical birth cohort
Project Code MRCPHS25Br Stergiakouli Research Theme Population Health Sciences Project Summary Download Summary This project will provide in-depth training in genetic epidemiology, childhood mental health, cohort studies and cleft. The student will have the opportunity to develop into one of…
Quantifying the impact of chronic pesticide exposure on disease susceptibility
Project Code MRCPHS25Br Siviter Research Theme Population Health Sciences Project Summary Download Summary Humanity has endured several outbreaks of infectious diseases that threaten population health. Environmental factors can influence disease susceptibility, but quantifying the impact of specific stressors is extremely…