Project Code MRCIIAR25Br Mann Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This project addresses the ongoing challenge posed by HIV-1, a virus infecting approximately 38 million people globally, with Subtype C (C-HIV) as the most…
Developing new weapons to fight drug-resistant superbugs – targeting lipoteichoic acid biosynthesis
Project Code MRCIIAR25Br Laabei Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antimicrobial resistance (AMR) has been described as the silent pandemic, fuelled in part by insufficient antibiotic development. We have identified novel small molecules that…
Emerging co-resistance to first and second line antibiotics in urinary pathogens and implications for the control of urosepsis.
Project Code MRCIIAR25Br Avison Research Theme Infection, Immunity, Antimicrobial Resistance and Repai Project Summary Download Summary Reducing antibiotic resistance (ABR) among urosepsis pathogens – derived from urinary tract infection (UTI) via pyelonephritis – is central to the UKs ABR-reduction strategy.…
Investigating the role of dietary fructose in the development of early-onset colorectal cancer
Project Code MRCPHS24Br Vincent Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Alarmingly, the incidence of early-onset colorectal cancer (EOCRC) is increasing…
Investigating cause-specific hospitalisations among people living with HIV on antiretroviral therapy
Project Code MRCPHS24Br Trickey Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary This project aims to investigate rates of hospitalisations due to…
Using genetics to understand mental health outcomes in children from a clinical birth cohort
Project Code MRCPHS24Br Stergiakouli Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary This project will provide in-depth training in genetic epidemiology, childhood…
Exploring the interplay and mechanisms between sleep, circadian rhythms and physical activity for improved physical and mental health
Project Code MRCPHS24Br Richmond Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Understanding the interplay between physical activity and sleep is important…
Genomic Surveillance Meets Machine Learning: Predicting the Origins of Salmonella Outbreaks with Machine Learning
Project Code MRCPHS24Br Reyher Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Gastrointestinal disease caused by the consumption of contaminated food is…
Harnessing the genetics of DNA methylation to understand context-specific gene regulation in disease
Project Code MRCPHS24Br Min Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Many disease risk factors have genetic and environmental influences. DNA…
Exploring the value of using large third-party artificial intelligence models in epidemiology, with examples using Twitter data
Project Code MRCPHS24Br Millard Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Large language models (LLMs) are an artificial intelligence approach that…