Project Code MRCIIAR26Ex Ball Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Environmental microplastics are a human health concern. Ingestion/inhalation have been thought to be the predominant routes into the human body,…
Decoding Lupus: using liquid biopsies to understand autoimmunity
Project Code MRCIIAR26Ex Cano-Gamez Project Type Mixed (50% wet lab, 50% dry lab) Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Lupus is a serious autoimmune disease where the immune system attacks the body’s own cells.…
Developing antibiotic potentiators against highly antibiotic resistant human pathogens using the model organism Galleria Mellonella
Project Code MRCIIAR26Ex Harmer Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antimicrobial resistance is an increasing societal issue, contributing to ~5,000,000 deaths in 2019. The highest priority bacterial pathogens account for…
Uncovering new genetic mechanisms of beta-cell autoimmunity to better understand type 1 diabetes
Project Code MRCIIAR26Ex Johnson Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This project uses a unique collection of samples from people with diabetes to address a fundamental question: What are the…
Decoding the pharmaceutical potential of mistletoe
Project Code MRCIIAR26Ex Nuetzmann Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Microbial infections threaten our health and kill millions worldwide. In this project, we will deploy cutting edge biochemistry, genomics, and…
Will climate change worsen the problem of antibiotic resistance?
Project Code MRCIIAR26Ex Padfield Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Recent studies have shown that levels of antimicrobial resistance (AMR) increase at higher environmental temperatures, but we have limited understanding…
Establishing a humanised zebrafish model for studying the genetic resilience in Neurofibromatosis Type 1 (NF1)
Project Code MRCIIAR26Ex Scholpp Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary This PhD project explores the phenomenon of “genetic resilience” in the context of Malignant Peripheral Nerve Sheath Tumours (MPNSTs), aggressive…
Developing CRISPR-Cas antimicrobials to tackle antibiotic resistance spread in Klebsiella pneumoniae
Project Code MRCIIAR26Ex van Houte Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antimicrobial resistance (AMR) poses a major threat to human health, which is for a large part driven by plasmids…
Novel phage-based therapeutics against drug-resistant bacteria
Project Code MRCIIAR26Ex Westra Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Antibiotic-resistant Pseudomonas aeruginosa is a major global health threat, causing infections that are increasingly difficult to treat. This project will…
Quantifying Rapid Evolution of Thermal Tolerance in the Novel Pathogenic Fungus Candida auris (Candidozyma auris)
Project Code MRCIIAR26Ex Yvon-Durocher Project Type Wet lab Research Theme Infection, Immunity, Antimicrobial Resistance and Repair Project Summary Download Summary Periodic episodes of high temperature associated with global climate change may be driving changes in the host range of pathogens,…