Project Code MRCNMH25Ex Witton Research Theme Neuroscience & Mental Health Project Summary Download Summary Microglia are brain-resident immune cells. Alongside conventional molecular signals, the latest research suggests that specific patterns of brain activity can control microglia function. We have found…
Metabolic psychiatry – Understanding ethnic and global differences in the inter-relationships between obesity and mental health
Project Code MRCNMH25Ex Tyrrell Research Theme Neuroscience & Mental Health Project Summary Download Summary Many people live with multiple health conditions, but research still tends to focus on individual diseases. This project, focuses on two global health problems with a…
Exploiting lipid binding proteins to tackle neurological disorders
Project Code MRCNMH25Ex Schrader Research Theme Neuroscience & Mental Health Project Summary Download Summary This multi-disciplinary project combines cutting-edge molecular cell biology, neurobiological, and biochemical (lipid analysis) approaches to reveal novel links between organelle membrane proteins, lipid metabolism, and neurodegenerative…
Assuming associations from old data- the case of ADHD and drug use
Project Code MRCNMH25Ex Russell Research Theme Neuroscience & Mental Health Project Summary Download Summary Many research papers about ADHD include the sentence “ADHD is associated with increased risk of substance use”. However, new analysis in UK datasets has shown no…
Using machine learning to classify microglia
Project Code MRCNMH25Ex Richards Research Theme Neuroscience & Mental Health Project Summary Download Summary During this exciting, fully-funded PhD, you will use machine learning to automatically classify the state of microglia (the brain’s specialised immune cells). This will involve combining…
Mapping Preterm Sleep Microstructure and EEG Biomarkers for Early Neurodevelopmental Risk Assessment
Project Code MRCNMH25Ex Poorun Research Theme Neuroscience & Mental Health Project Summary Download Summary Sleep is crucial for early brain development, yet preterm infants often have disrupted sleep patterns that may impact their long-term outcomes. This project will use advanced…
Development and characterisation of reproducible complex human brain organoids – Bio-engineering and neuronal networks
Project Code MRCNMH25Ex Piers Research Theme Neuroscience & Mental Health Project Summary Download Summary Using induced pluripotent stem cells, we can generate complex multi-cellular 3D human brain tissue models in a dish, termed cerebral organoids. These models provide unique opportunities…
AI-Powered Fatigue Solutions: Transforming Care for Neurological Conditions
Project Code MRCNMH25Ex Mansoubi Research Theme Neuroscience & Mental Health Project Summary Download Summary Fatigue is a major issue for individuals with neurological conditions, often leading to lower quality of life. This project aims to empower these individuals through an…
What is it like to have advanced dementia? Using remote measurement of EEG and physiological markers of sleep, arousal and awareness in people with advanced Alzheimer’s disease
Project Code MRCNMH25Ex Huntley Research Theme Neuroscience & Mental Health Project Summary Download Summary What is it like to have advanced dementia? How do changes in sleep and awareness impact the behaviour and quality of life of people living with…
Understanding motor neuron disease using a powerful combination of model systems
Project Code MRCNMH25Ex Housden Research Theme Neuroscience & Mental Health Project Summary Download Summary The aim of this project is to understand the mechanisms that cause motor neuron disease (MND) so that new treatments can be developed. This is important…