Project Code
MRCIIAR25Ex Schlopp
Research Theme
Cross-Cutting
Infection, Immunity, Antimicrobial Resistance and Repair
Neuroscience and Mental Health
Population Health Sciences
Project Summary Download
Summary
Cells communicate by sending signals that cause receiving cells to change their behaviour. In response to such a signal, cells will adopt a specific fate or start to divide. Failure to properly control cell signalling, for example, if the wrong cells receive the signal, causes diseases such as cancer. Wnt signalling is a critical pathway controlling cell behaviour in development and diseases. In this project, we will decipher why specific cells can respond to Wnt signals whereas others do not. This knowledge is essential to understand embryogenesis and tissue homeostasis and, consequently, to control many diseases.
Lead Supervisor
Professor Steffen Scholpp
Lead Supervisor Email
s.scholpp@exeter.ac.uk
University Affiliation
Exeter