Project Code
MRCIIAR25Ba Iqbal
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
Bacteria have been engaged in a war with the viruses that predate on them (“phage”) for millions of years, both sides developing defence/counter-defence systems. We humans would like to use phage as an alternative to antibiotic therapy, but it is hard to decide which phage will successfully kill a specific bacterial strain, in the light of the huge diversity of defence/counter-defence systems. This project set out to apply statistical and modern AI methods to rich new experimental datasets, to build a deeper understanding of the interactions between bacteria and phage and discover how their defence systems work and interact.
Lead Supervisor
Professor Zamin Iqbal
Lead Supervisor Email
zi245@bath.ac.uk
University Affiliation
Bath