Determining the potential human health impacts of microplastic contamination via direct injection, a novel exposure route for MP from medicinal products

Project Code

MRCIIAR26Ex Ball

Project Type

Wet lab

Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Project Summary Download

Summary

Environmental microplastics are a human health concern. Ingestion/inhalation have been thought to be the predominant routes into the human body, but do medicinal products provide a third route via direct injection? In 2025 IV bags were shown to shed microplastics internally and therefore are they and other medicinal products a direct source of human microplastics contamination and adverse drug interaction? The student will investigate distribution, host immune and innate interaction with medicinal microplastics and simultaneous drug exposure. Using high content imaging systems, focusing on development and musculoskeletal systems in zebrafish to determine if medical microplastics are an unrecognised health hazard.

Lead Supervisor

Dr Jonathan Ball

Lead Supervisor Email

j.ball@exeter.ac.uk

University Affiliation

Exeter