Exploring the epigenetic links between genes, environment and health

Project Code

MRCPHS26Br Min

Project Type

Dry lab

Research Theme

Population Health Science

Project Summary Download

Summary

How do cells respond to environmental exposures? How do these exposures interact with genetic factors to influence disease risk? This PhD project investigates the interplay between genetics, environmental exposures, and epigenetics with a focus on DNA methylation as a key mechanism of gene regulation.
You will:

  • Apply genetic epidemiology and population health data science approaches on large epidemiological datasets
  • Identify gene-environment interactions that influence DNA methylation patterns
  • Explore how these interactions contribute to disease risk with Mendelian randomization
    Apply now to join an international research team and uncover biological mechanisms that link environmental factors to disease risk.

Lead Supervisor

Dr Josine Min

Lead Supervisor Email

josine.min@bristol.ac.uk

University Affiliation

Bristol