How does the membrane environment impact the activity of the µ-opioid receptor?

Project Code

MRCNMH24Br Corey

Research Theme

Neuroscience and Mental Health

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.


This project will use cutting-edge computational methods to understand how the membrane and cellular localisation impact the activity of the µ-opioid receptor, including how it binds and is activated by different opioid drugs. Along with wet lab functional data gathered with co-supervisors, these findings will generate insights into opioid receptor signalling and pave the way for future therapeutic breakthroughs in both the management of pain and opioid addiction.

Lead Supervisor

Dr Robin Corey

Lead Supervisor Email

University Affiliation