Deciphering how NLRP3 inflammasome- and STING-driven inflammatory pathways are linked to mental health disorders

Project Code MRCNMH24Ca Triantafilou Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary There is an interaction between activation of the innate…

Stem cells and hungry neurons: neuropeptides in energy homeostasis

Project Code MRCNMH24Ca Petrik Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary You will investigate the role of neural stem cells…

Developing a new therapeutic strategy for brain cancers: getting therapeutics directly to the tumour

Project Code MRCNMH24Ca Newland Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Some brain cancers cannot be surgically removed, and many…

A multimodal investigation of brain structure and function in schizophrenia

Project Code MRCNMH24Ca McNabb Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Aberrant brain structure and function are implicated in the…

AI and structure based drug discovery of chaperones for misfolded lysosomal enzymes involved in neurodegenerative disease

Project Code MRCNMH24Ca Lloyd-Evans Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary A major risk gene for Parkinson disease encodes a…

What goes up must come down? Using digital technology to understand the dynamic nature of mood in bipolar disorder

Project Code MRCNMH24Ca Lewis Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary People with bipolar disorder (BD) experience disabling episodes of…

Maternal anxiety and language delays in children – both outcomes of the same epigenetic alteration?

Project Code MRCNMH24Ca John Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Maternal depression and anxiety are highly common in pregnancy…

How does the schizophrenia candidate gene Sp4 influences transcription during neurodevelopment?

Project Code MRCNMH24Ca Isles Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Both common and rare variants in the gene encoding…