Project Code MRCNMH26Ca Ngo Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Neurodevelopmental disorders (NDDs) like autism and ADHD affect millions, yet the underlying causes remain unclear. This PhD project investigates how mutations in…
Novel area-modulation stimuli for identifying changes in visual field sensitivity in Age-related Macular Degeneration (AMD)
Project Code MRCNMH26Ca Redmond Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Age-related macular degeneration (AMD) is one of the world’s leading causes of sight loss. Traditional measures of vision in AMD are of…
When DNA Breaks and Mitochondria Fail: Investigating Drivers of Huntington’s Disease
Project Code MRCNMH26Ca Smith Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Huntington’s disease (HD) is a fatal inherited brain disorder with no effective treatment. It causes specific neurons in the brain to degenerate,…
Pain as neurobiological surprise: Using human brain imaging and animal studies to advance new concepts in persistent pain.
Project Code MRCNMH26Ca Tackley Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Complex nervous systems attempt to minimise surprise and aid survival by forming predictions about the world. Surprise signals danger: it is evidence…
Maternal anxiety and language delays in children – both outcomes of the same epigenetic alteration?
Project Code MRCNMH25Ca John Research Theme Neuroscience and Mental Health Project Summary Download Summary Maternal depression and anxiety are highly common in pregnancy and associated with a negative effect on the child’s social and language skills. This PhD will test…
Recognising uniquely human emotions
Project Code MRCNMH25Ca von dem Hagen Research Theme Neuroscience & Mental Health Project Summary Download Summary Being able to read other people’s emotions can convey considerable social benefits. But it remains unclear how humans perceive others’ uniquely human emotions (such…
Biomarker discovery of inflammatory pathways linked to mood and autoimmune disorders
Project Code MRCNMH25Ca Szomolay Research Theme Neuroscience & Mental Health Project Summary Download Summary “Mood disorders (MDs), e.g. depression, affect over one billion people worldwide. MDs show a bidirectional relationship with systemicinflammation, a key component in the pathophysiology of autoimmune…
How does DNA damage and mitochondrial dysfunction contribute to Huntington’s disease?
Project Code MRCNMH25Ca Smith Research Theme Neuroscience & Mental Health Project Summary Download Summary Huntington’s disease (HD) is an inherited disorder that causes specific neurons in the brain to die. HD patients develop uncontrollable movements as well as cognitive and…
AI-enhanced Quantitative MRI for Multi-Scale Multi-Modal Neuroscience
Project Code MRCNMH25Ca Slator Research Theme Neuroscience & Mental Health Project Summary Download Summary This project will develop advanced machine learning methods for medical imaging to non-invasively characterise brain tissue structure and function. The project focuses on quantitative MRI, which…
Enabling continuous, personalised stress quantification and management with a wearable system
Project Code MRCNMH25Ca Pham Research Theme Neuroscience & Mental Health Project Summary Download Summary Nine in ten adults in the UK suffer from high or extreme stress in 2023. Stress-related disorders and burnout cost the UK economy more than £28…