Developing a new therapeutic strategy for brain cancers: getting therapeutics directly to the tumour

Project Code MRCNMH25Ca Newland Research Theme Neuroscience & Mental Health Project Summary Download Summary Some brain cancers cannot be surgically removed, and many potent therapeutics cannot reach the tumour site. This project aims to overcome these hurdles by utilizing a…

Unravelling the Pharmacological Activation of PINK1, a Protein Kinase Mutated in Parkinson’s Disease

Project Code MRCNMH25Ca Mehellou Research Theme Neuroscience & Mental Health Project Summary Download Summary “Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are limited to addressing the symptoms of…

Using MRI, MEG, and machine learning to better classify severe mental illness

Project Code MRCNMH25Ca McNabb Research Theme Neuroscience & Mental Health Project Summary Download Summary Clinical diagnoses of severe mental illnesses currently rely solely on symptom report and poorly predict long-term outcomes. This PhD project aims to integrate information from brain…

Using a new translational in vivo model to understand the neurobiology underlying ADHD subtypes

Project Code MRCNMH25Ca Davies  Research Theme Neuroscience & Mental Health Project Summary Download Summary In mice and humans loss-of-function of the steroid sulfatase (STS) enzyme results in inattention but enhanced motor response inhibition; we aim to understand the neurobiology underlying…

Unlocking the causes of eating disorders: investigating risk factors across development

Project Code MRCNMH25Ca Chawner Research Theme Neuroscience & Mental Health Project Summary Download Summary Tackling eating disorders is of growing importance in society, with increasing numbers of children and young people referred to eating disorder services. This PhD project focuses…

Deciphering how NLRP3 inflammasome- and STING-driven inflammatory pathways are linked to mental health disorders

Project Code MRCNMH24Ca Triantafilou Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary There is an interaction between activation of the innate…

Stem cells and hungry neurons: neuropeptides in energy homeostasis

Project Code MRCNMH24Ca Petrik Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary You will investigate the role of neural stem cells…

Developing a new therapeutic strategy for brain cancers: getting therapeutics directly to the tumour

Project Code MRCNMH24Ca Newland Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Some brain cancers cannot be surgically removed, and many…