Project Code CMD27Ex Beaumont Project Type Dry lab Research Theme Cardiometabolic Disease Project Summary Download Summary Diabetes is a highly heterogeneous condition, but its clinical management relies heavily on HbA1c – a biomarker affected by distinct pathways: glucose metabolism (glycaemic)…
Data-Driven Precision Medicine in the Hospital: Advanced Blood Glucose Analytics to Improve Inpatient Diabetes Care
Project Code CMD27Ex Dennis Project Type Dry lab Research Theme Cardiometabolic Disease Project Summary Download Summary 20%-30% of NHS hospital beds are occupied by people with diabetes, who often experience poorer clinical outcomes due to unstable blood sugar levels (adverse…
Understanding the causes, and best treatment, of type 2 diabetes in people who are not overweight
Project Code CMD27Ex Jones Project Type Dry lab Research Theme Cardiometabolic Disease Project Summary Download Summary Many people think of type 2 diabetes as being a condition that affects people with high body weight, but millions of people with type…
Genetic and Therapeutic Determinants of Adverse Drug Reactions in Cardio-Renal Diseases
Project Code CMD27Ex Pilling Project Type Dry lab Research Theme Cardiometabolic Disease Project Summary Download Summary Why do people with cardiometabolic diseases experience different health trajectories despite similar treatment? This interdisciplinary PhD project will investigate how genetic variation, prescribing, and…
Metabolic adaptation to a low carbohydrate ketogenic diet and its effects on exercise fuel use and glucose management in physically active people with Type 1 Diabetes
Project Code CMD27Ex Podlogar Project Type Wet lab Research Theme Cardiometabolic Disease Project Summary Download Summary Ketogenic diet (very low in carbohydrate, high in fat) is increasingly popular among people with Type 1 Diabetes (T1D). In principle, a ketogenic diet…
Understanding Muscle Metabolism Responses to Feeding in Adult Survivors of Childhood Acute lymphoblastic Leukaemia
Project Code CMD27Ex Revuelta Iniesta Project Type Wet lab Research Theme Cardiometabolic Disease Project Summary Download Summary Survivors of childhood acute lymphoblastic leukaemia (ALL) experience premature frailty (age 44) defined by muscle atrophy. Muscle protein synthesis is crucial for muscle…
Sex-Specific Cardiac Remodelling in Female Athletes: Unravelling Cardiometabolic Risk and Long-Term Health Outcomes
Project Code CMD27Ex Williams Project Type Wet lab Research Theme Cardiometabolic Disease Project Summary Download Summary This project tackles a major challenge in biomedical research: the historical under-representation of women in cardiovascular and sports science. Much of what we know…
Cracking the Host-Pathogen Metabolic Code in Tuberculosis: Discovering New Therapeutic Strategies
Project Code IIAR27Ex Borah Slater Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Tuberculosis (TB) remains one of the world’s leading infectious killers, with the urgent need for new treatments. This exciting PhD…
Phage Power: Optimising Treatments for Bacterial Co-Infections
Project Code IIAR27Ex Castledine Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary As antibiotic resistance threatens modern medicine, phage therapy is emerging as a powerful new weapon against bacterial infections. These naturally occurring…
How does temperature shape selection for resistance across different antibiotics, strains, and species
Project Code IIAR27Ex Padfield Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Climate warming is linked to rising antimicrobial resistance (AMR), but the biological mechanisms remain poorly understood. This project asks how temperature…