How does temperature shape selection for resistance across different antibiotics, strains, and species

Project Code

IIAR27Ex Padfield

Project Type

Wet lab

Research Theme

Infection, Immunity, and Antimicrobial Resistance

Project Summary Download

Summary

Climate warming is linked to rising antimicrobial resistance (AMR), but the biological mechanisms remain poorly understood. This project asks how temperature shapes selection for resistance across different antibiotics, strains, and species of Klebsiella, a clinically important pathogen. Combining eco-evolutionary theory, lab experiments, and genomic sequencing, you will help build and validate a model predicting how antibiotic selection shifts with temperature — advancing our ability to control AMR in a warmer world.

Can the project be completed part time?

Yes

Lead Supervisor

Dr Daniel Padfield

Lead Supervisor Email

d.padfield@exeter.ac.uk

University Affiliation

University of Exeter

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