Project Code IIAR27Ex van Houte Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antimicrobial resistance (AMR) poses a major threat to human health, which is for a large part driven by plasmids (mobile…
How pathogens emerge: integrating large language models with comparative genomics to uncover the zoonotic potential of bacteria
Project Code IIAR27Ex Vos Project Type Dry lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Most emerging bacterial pathogens originate from animal hosts (are ‘zoonotic’), yet it is hard to predict which pathogen species are likely…
Bacterial pathogen evolution during antibiotic-phage combination treatment
Project Code IIAR27Ex Westra Project Type Wet lab Research Theme Infection, Immunity, and Antimicrobial Resistance Project Summary Download Summary Antimicrobial resistance is a major threat to modern medicine, and bacteriophage therapy is a promising route to treat drug-resistant infections. Yet…
Cracking the ribosome code of brain development
Project Code NMH27Ex Bernard Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary What if ribosomes carried a code that helps build the brain? Ribosomes are complex molecular structures that play active roles in protein…
Communication Breakdown: Using human 3D bioprinted models to understand disruption of neuron-muscle interactions in ALS
Project Code NMH27Ex Bhinge Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary ALS is a devastating neurological disease with no cure, and we urgently need new ways to understand and treat it. This exciting…
Developing Blood Tests for the Early Detection of Neurodegeneration Following Traumatic Brain Injury
Project Code NMH27Ex Dempster Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Traumatic brain injury (TBI), including repetitive head impacts during contact sports, increases the risk of developing later-life neurodegenerative diseases such as chronic…
AI scientists for understanding dementia modifiable risk factors
Project Code NMH27Ex Dong Project Type Dry lab Research Theme Cardiometabolic Disease Infection, Immunity, Antimicrobial Resistance and Repair Neuroscience and Mental Health Population Health Science Project Summary Download Summary Early dementia prediction is an urgent problem to improve the clinical…
Turning off transcription factors to understand what happens first in neurodevelopmental disorders
Project Code NMH27Ex Flynn Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary What are the first things that go wrong in neurodevelopmental disorders? This project will use human stem cells to grow early brain…
Air Pollution, Heat and Other Environmental Exposures in Relation to Cognitive Ageing: A Longitudinal Cohort Study
Project Code NMH27Ex HZhang Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary How do the environments we live in influence how our brains age? This PhD will use the PROTECT study, a large UK…
Using sleep-based memory cues to support recovery from stressful memories
Project Code NMH27Ex Karl Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Many people who experience trauma go on to develop PTSD, and while talking therapies are effective, not everyone fully recovers. We examine…