The Contribution of Mitochondrial Dysfunction to Alzheimer’s disease

Opening date: Tuesday 2nd April 2024
Closing date: Wednesday 1st May 2024 at 5pm
Project Code MRC24NMHCa

Opening date: Tuesday 2nd April 2024
Closing date: Wednesday 1st May 2024 at 5pm

Open to: Home and international applicants
Application form: Click here to apply

For more information on how to apply and available support, please see our Student Application pages. Please note, some dates shown may apply to our main recruitment round. For a timeline on this additional round, please see the Application Pack below.

Project Code

MRC24NMHCa Smith

Research Theme

Neuroscience and Mental Health

Project Summary Download

Summary

Alzheimer’s disease (AD) is associated with increased oxidative stress and mitochondrial dysfunction in the brain. The Redox system that helps detoxify neurons is decreased in AD patients and likely contributes to symptoms and neurodegeneration. The PhD student will manipulate Redox and mitochondrial regulating genes in Drosophila and iPSC neuron models of AD to find new potential therapeutic targets.

Lead Supervisor

Dr Gaynor Ann Smith

Lead Supervisor Email

SmithGA@cf.ac.uk

University Affiliation

Cardiff