Project Code NMH27Ca Siebzehnrubl Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary How do glioblastoma stem cells evade therapy and drive tumour recurrence? This project will address this question by investigating how FGF2-FGFR1 signalling regulates…
Silent Architects: Uncovering How Astrocytes Shape Brain Health
Project Code NMH27Ca Smith Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Astrocytes are central regulators of brain function, controlling neuronal activity, metabolism, extracellular matrix organisation and resilience to disease. However, many astrocyte-enriched genes…
Chronic pain, sensory hypersensitivity and neurodiversity: why are they linked?
Project Code NMH27Ca Sumner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Chronic pain conditions such as fibromyalgia, dysmenorrhea and back pain affect millions of people and severely disrupt daily life. An interesting but…
Mapping Cerebellar Network Dysfunction in Episodic Ataxia Using Human Organoids
Project Code NMH27Ca Syed Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary This project investigates how mutations in the KCNA1 gene cause Episodic Ataxia Type 1 (EA1), a rare neurological disorder characterised by impaired…
Pain as neurobiological surprise: Using human brain imaging and animal studies to advance new concepts in persistent pain.
Project Code NMH27Ca Tackley Project Type Other Research Theme Neuroscience and Mental Health Project Summary Download Summary We experience surprise when our best guess about the immediate future turns out to be wrong. This can be dangerous: it might mean…
Neural Dynamics of Perceptual Decision-Making During Robot-Mediated Motor Learning
Project Code NMH27Ca Zhou Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary How does the brain make decisions while we are moving and learning? This PhD project will combine EEG, virtual reality and robotic…
Unlocking the causes of eating disorders: investigating risk factors across development
Project Code MRCNMH25Ca Chawner Project Type Dry lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Tackling eating disorders is of growing importance in society, with increasing numbers of children and young people referred to eating disorder services.…
A High-Efficiency and Sustainable Next-Generation Nanotherapeutic platform to Improve Astrocytoma Outcomes
Project Code MRCNMH26Ca Duc Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary In 2023, the Welsh and UK Government emphasised the urgent need for astrategic plan prioritising research in brain tumour therapy. Astrocytoma,comprising 1/3…
How ADHD affects curiosity and curiosity-based learning
Project Code MRCNMH26Ca Gruber Project Type The project will combine behavioural and neuroimaging studies (in particular, functional Magnetic Resonance Imaging, fMRI) in human participants. Research Theme Neuroscience and Mental Health Project Summary Download Summary This PhD project explores how curiosity…
SONIC-Glaucoma: Stimulation Of Neuroprotective & Immunomodulatory Cargos via Ultrasound in Glaucoma
Project Code MRCNMH26Ca Mead Project Type Wet lab Research Theme Neuroscience and Mental Health Project Summary Download Summary Glaucoma causes progressive retinal ganglion cell (RGC) loss and remains without effective neuroprotective therapy. While platelet-derived growth factor (PDGF) and brain-derived neurotrophic…