Pain as neurobiological surprise: Using human brain imaging and animal studies to advance new concepts in persistent pain.

Project Code

NMH27Ca Tackley

Project Type

Other

Research Theme

Neuroscience and Mental Health

Project Summary Download

Summary

We experience surprise when our best guess about the immediate future turns out to be wrong. This can be dangerous: it might mean tripping on an unexpectedly loose stone, or underestimating the temperature of a saucepan and burning your hand. Thus, to survive, animals are constantly in the business of minimising surprise. This PhD will test the idea that pain is a form of neurobiological surprise, specifically signalling unexpected threat or damage. This will be explored using human neuroimaging and rodent studies, evaluating the influence of conscious and unconscious predictions, and investigating the maintenance of persistent (chronic) pain states.

Can the project be completed part time?

Yes

Lead Supervisor

Dr George Tackley

Lead Supervisor Email

tackleyg@cardiff.ac.uk

University Affiliation

Cardiff University

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