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Investigating the role of extracellular vesicles in influencing inflammation during tissue regeneration in zebrafish

Project Code

MRCIIAR24Br RichardsonR

Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.

MRCIIAR24Br-RichardsonR

Summary

Zebrafish have a remarkable ability to regenerate damaged tissues. Tissue repair and regeneration requires communication between multiple different cell types including immune cells, fibroblasts and endothelial cells. Extracellular vesicles (EVs) deliver molecular messages between cells and our data suggests they promote regeneration. This project will determine how EVs might be harnessed to facilitate optimal repair of damaged tissues via influencing inflammation.

Lead Supervisor

Dr Rebecca Richardson

Lead Supervisor Email

rebecca.richardson@bristol.ac.uk

University Affiliation

Bristol