Novel digital diagnostics for antimicrobial resistance based on ion-channel communication

Project Code

MRCIIAR26Ba Reis

Project Type

Dry lab

Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Project Summary Download

Summary

Bacterial infections affect millions of people worldwide. Current methodologies for bacterial identification and antibiotic susceptibility testing (AST) are time consuming or unable to inform about antimicrobial resistance (AMR). Critically, most patients lack access to sophisticated and near-the-patient microbiological laboratories, which means being not properly treated or prescribed unnecessary antibiotics, key drivers of global AMR. This project will pioneer optical and electrical signal detection of bacteria communication through ion channels with microfluidic devices and machine learning for developing a transformative approach to AST in pathogen bacteria in human samples . This will pave a new way to personalised and effective medicine.

Lead Supervisor

Dr Nuno Reis

Lead Supervisor Email

n.m.reis@bath.ac.uk

University Affiliation

Bath