Project Code
MRCPHS26Ex Kudoh
Project Type
Wet lab
Research Theme
Population Health Science
Project Summary Download
Summary
Foetal Alcohol Spectrum Disorder (FASD) occurs via alcohol consumption in pregnancy with 1-5% frequency in humans, causing distinctive facial features alongside brain development defects. In this interdisciplinary project, we will use the zebrafish embryo as an animal model for FASD and utilise human data with epidemiological approaches, linking phenotype of FASD with epigenetic ‘omic data (DNA methylation). The data will be utilised for improving detection of prenatal alcohol exposure and fetal alcohol spectrum disorder and designing targeted therapies to improve outcomes.
Lead Supervisor
Dr Tetsuhiro Kudoh
Lead Supervisor Email
University Affiliation
Exeter