Project Code
MRCIIAR25Ca McLaren
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
There is no licenced vaccine against Staphylococcus aureus which produces life-threatening bloodstream infections (“bacteraemia”) and has evolved antibiotic-resistant strains. However, mucosal-associated invariant T (MAIT) cells can combat certain antibiotic-resistant bacteria, positioning them as ideal targets for new vaccines. The student will examine how MAIT cell responses against Staphylococcus aureus are affected by the bacterium during bacteraemia.
Lead Supervisor
Dr James McLaren
Lead Supervisor Email
mclarenje@cardiff.ac.uk
University Affiliation
Cardiff