Integrative analysis of whole genomes and transcriptomes from multiple cell types in rare disease patients

Project Code MRCPHS24Ex Frontini Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary The use of Whole-Genome Sequencing increased the diagnostic yield for…

Understanding how ethnic differences may influence diabetes diagnosis and control in pregnancy

Project Code MRCPHS24Ex Freathy Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary When diabetes occurs in pregnancy, monitoring of maternal glucose is…

Investigating the epigenetic component of insulin secretion disorders

Project Code MRCPHS24Ex Dempster Research Theme Population Health Sciences Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary During this PhD, you will use innovative bioinformatic techniques to…

Characterising a novel neuroimmune pathway to treat neurodegenerative disease

Project Code MRCNMH24Ex Witton Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Microglia are brain-resident immune cells. Alongside conventional molecular signals,…

Can nutritional intervention unlock better outcomes after traumatic brain injuries? Investigating brain blood flow and cellular metabolism regulation by ketones following head impacts

Project Code MRCNMH24Ex Weightman Potter Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary This project will investigate the efficacy of ketogenic…

Metabolic psychiatry – Understanding ethnic and global differences in the inter-relationships between obesity and mental health

Project Code MRCNMH24Ex Tyrrell Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Many people live with multiple health conditions, but research…

Developing computational models of psychosis to explore the impact of schizophrenia-associated CNVs on cortical microcircuitry

Project Code MRCNMH24Ex Shaw Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary Breakthroughs in genetics have identified specific CNVs that substantially…

“You must be on your period”: using smartphones and wearables to study changes in mental wellbeing throughout the menstrual cycle

Project Code MRCNMH24Ex Sharp Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary The menstrual cycle can influence mental wellbeing for a…

Exploiting lipid binding proteins to tackle neurological disorders

Project Code MRCNMH24Ex Schrader Research Theme Neuroscience and Mental Health Full Project Description Please download the below document for a full project description and to see the full supervisory team. Summary This multi-disciplinary project combines cutting-edge molecular cell biology, neurobiological,…