Neuroscience and Mental Health
Full Project Description
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Breakthroughs in genetics have identified specific CNVs that substantially increase risk for schizophrenia. These CNVs impact NMDA & GABAA receptors, but how this disrupts cortical function is unknown. You will develop computational models that capture changes in NMDA and GABA receptor dynamics in CNV carriers. These models will be applied to existing neuroimaging (MEG) and cognitive data to make novel insights connecting genetics to brain function and cognition.
Dr Alexander Shaw
Lead Supervisor Email