Project Code
MRCNMH24Br Ashby
Research Theme
Neuroscience and Mental Health
Full Project Description
Please download the below document for a full project description and to see the full supervisory team.
Summary
Schizophrenia is a severe neurodevelopmental psychiatric disorder with high heritability, but we don’t know how genetic variation leads to abnormal maturation of brain function. Disruption of the SETD1A gene is linked to elevated schizophrenia risk. In this project, we will investigate the cortical development of a mouse model of SETD1A deficiency using molecular, electrophysiological, imaging and behavioural techniques to link aberrant neurobiology to pathology.
Lead Supervisor
Dr Michael Ashby
Lead Supervisor Email
m.c.ashby@bristol.ac.uk
University Affiliation
Bristol