Project Code
MRCIIAR26Br Armstrong
Project Type
Wet lab
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
Biomaterials can be used to regenerate diseased or damaged tissues. Substantial progress has been made in our understanding of the biochemical and biophysical cues that promote functional tissue repair. However, an often-overlooked aspect is innervation: the ability of the biomaterial to support the growth of integrated nerve fibers throughout the newly formed tissue. This PhD project will address this challenge by producing a suite of regenerative hydrogels with different biochemical and biomechanical characteristics and screening their ability to support innervation using in vitro tissue engineering and in vivo zebrafish models.
Lead Supervisor
Dr James Armstrong
Lead Supervisor Email
University Affiliation
Bristol