Project Code
MRCIIAR26Ex Johnson
Project Type
Wet lab
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
This project uses a unique collection of samples from people with diabetes to address a fundamental question: What are the genetic mechanisms underpinning beta-cell autoimmunity?
Over a century since the discovery of insulin, and four decades since the recognition that type 1 diabetes (T1D) is an autoimmune disease, the mechanisms underlying T1D remain unsolved.
By identifying new genetic forms of autoimmune diabetes, you will develop a powerful combination of skills in genomics, immunology, and clinical research, providing new diagnoses to these families and uncover new mechanisms of beta-cell destruction – the first step towards the ultimate goal of preventing T1D.
Lead Supervisor
Dr Matthew Johnson
Lead Supervisor Email
University Affiliation
Exeter