Understanding early and midlife causes of cardiovascular disease through genetics

Project Code

MRCPHS26Br Sanderson

Project Type

Dry lab

Research Theme

Population Health Science

Project Summary Download

Summary

Cardiovascular disease is a major cause of ill health in later life. However, development of this disease is likely to be influenced by traits throughout life. This project will use genetic epidemiology to explore methods to estimate how traits at different ages affect long-term disease risk. The project will make use of novel data on the association of genetic variants with traits at specific ages and trait trajectories. The student will gain experience with large-scale genetic data and develop skills in causal inference, statistical genetics, and population health, while addressing important questions in lifecourse epidemiology and chronic disease prevention.

Lead Supervisor

Dr Eleanor Sanderson

Lead Supervisor Email

eleanor.sanderson@bristol.ac.uk

University Affiliation

Bristol