Project Code
MRCNMH25Ca Mehellou
Research Theme
Neuroscience & Mental Health
Project Summary Download
Summary
“Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are limited to addressing the symptoms of this disease. Thus, there is a need for new and effective treatments for PD.
Recently, we discovered molecules that activate a protein kinase called PINK1, which is mutated in early-onset PD. In this project, we now aim to use a multidisciplinary approach, which spans biochemistry, biophysics and cell biology, to understand how these molecules activate PINK1. The advances achieved from this project will facilitate the future discovery of effective treatments for PD.”
Lead Supervisor
Dr Youcef Mehellou
Lead Supervisor Email
mehellouy1@cardiff.ac.uk
University Affiliation
Cardiff