How safe are antiseizure medications in pregnancy for conditions other than epilepsy?

Project Code

MRCPHS25Ba McGrogan

Research Theme

Population Health Sciences

Project Summary Download

Summary

Did you know that only 5% of medicines licensed in the UK have sufficient evidence about their safety in pregnancy? Women may be advised not to use medicines in pregnancy due to concerns about harm to their offspring. However, some conditions must be treated throughout pregnancy or a woman’s health deteriorates which can also have life changing impacts on her offspring. Evidence is vital to allay fears of harm and inform decision making. This PhD will use Big Data to determine safety of antiseizure medications used for conditions not regularly studied in pregnancy including migraine, neuropathic pain and bipolar. disorder.

Lead Supervisor

Dr Anita McGrogan

Lead Supervisor Email

am399@bath.ac.uk

University Affiliation

Bath