Project Code
MRCNMH26Ca Duc
Project Type
Wet lab
Research Theme
Neuroscience and Mental Health
Project Summary Download
Summary
In 2023, the Welsh and UK Government emphasised the urgent need for a
strategic plan prioritising research in brain tumour therapy. Astrocytoma,
comprising 1/3 of UK brain tumours, impact both children (mainly low-grade) and
adults (can be high-grade e.g. glioblastomas with poor survival), stressing the need
for better treatments and quality of life(QoL). This research aims to develop
innovative functionalized nanocellulose-isothiocyanate nanoparticles drug-
delivery platform (FNP) capable of effectively crossing the blood-brain-
barrier(BBB) due to distinctive electroactive properties and effectively inducing
targeted anti-tumoral effect on astrocytoma cells and favour neural regeneration.
We will also explore electrical stimulation for enhancing FNP drug-delivery
across BBB.
Lead Supervisor
Dr Daniela Duc
Lead Supervisor Email
University Affiliation
Cardiff