Project Code MRCPHS25Ca Kaouri Research Theme Population Health Sciences Project Summary Download Summary In-Vitro Fertilization is the primary treatment of infertility, with ~2.5 million cycles performed annually. Success rates are, however, declining partly due to waiting 5 days to select…
Targeted reprogramming of epigenetic signals for lung regeneration
Project Code MRCPHS25Ca Jurkowska Research Theme Population Health Sciences Project Summary Download Summary What most of us do naturally and take for granted – the breathing – 500 million people struggle with as they suffer from incurable lung disease. Epigenetic…
Improving Bruise Evidence Across Variations in Skin Tone Using Artificial Intelligence
Project Code MRCPHS25Ca Farnell Research Theme Population Health Sciences Project Summary Download Summary Bruises are often seen on victims of violence in accident and emergency departments or as part of paediatric examinations. Bruising predicts later hospitalisation and homicide. Collecting reliable…
Investigating the role of the microbiome in obesity-driven colorectal cancer development
Project Code MRCPHS25Br Wade Research Theme Population Health Sciences Project Summary Download Summary Alarmingly, the incidence of early-onset colorectal cancer (EOCRC) is increasing rapidly in the UK. This rise may be, in part, attributable to obesity but exactly how obesity…
Metabolomic characterisation of adiposity across the life course
Project Code MRCPHS25Br Timpson Research Theme Population Health Sciences Project Summary Download Summary Adiposity, measured by body mass index (BMI), is linked to a range of health outcomes, but the underpinning biology is less understood. Metabolomics (the large-scale study of…
Using genetics to understand mental health outcomes in children from a clinical birth cohort
Project Code MRCPHS25Br Stergiakouli Research Theme Population Health Sciences Project Summary Download Summary This project will provide in-depth training in genetic epidemiology, childhood mental health, cohort studies and cleft. The student will have the opportunity to develop into one of…
Quantifying the impact of chronic pesticide exposure on disease susceptibility
Project Code MRCPHS25Br Siviter Research Theme Population Health Sciences Project Summary Download Summary Humanity has endured several outbreaks of infectious diseases that threaten population health. Environmental factors can influence disease susceptibility, but quantifying the impact of specific stressors is extremely…
Exploring the interplay and mechanisms between sleep, circadian rhythms and physical activity in relation to physical and mental health
Project Code MRCPHS25Br Richmond Research Theme Population Health Sciences Project Summary Download Summary Understanding the interplay between physical activity and sleep is important for improving physical and mental health. A proposed mechanism linking physical activity with improved sleep is through…
Shining a light on the un-common to identify novel health risk-factors
Project Code MRCPHS25Br Nivard Research Theme Population Health Sciences Project Summary Download Summary Complex traits such as body mass index and height are influenced by a mixture of genetic and environmental factors. By first predicting what an individual’s BMI or…
Using diverse cohorts, methods and novel measures to understand the relationship between diet, physical activity and health outcomes
Project Code MRCPHS25Br Munafò Research Theme Population Health Sciences Project Summary Download Summary Certain aspects of diet (e.g., high salt intake) and lower physical activity are known to cause poorer health outcomes. However, the impacts of other specific food types…