Developing new weapons to fight drug-resistant superbugs – targeting lipoteichoic acid biosynthesis

Project Code

MRCIIAR24Ba Laabei

Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Full Project Description

Please download the below document for a full project description and to see the full supervisory team.


Antimicrobial resistance (AMR) is a major threat to global health. Lack of drug development severely hampers treatment options. We identified novel small molecules that target a crucial bacterial component called lipoteichoic acid. This interdisciplinary project will develop more stable and potent drug derivatives and further define the molecular activity of these compounds using a suite of chemical and molecular methods and invertebrate infection models.

Lead Supervisor

Dr Maisem Laabei

Lead Supervisor Email

University Affiliation