Developing precision guided, viral based therapies using machine learning approaches

Project Code

MRCIIAR26Ca Parker

Project Type

Wet lab

Research Theme

Infection, Immunity, Antimicrobial Resistance and Repair

Project Summary Download

Summary

The Viral ImmunoTherapies and Advanced Therapeutics Laboratory engineers “smart viruses” for targeted treatment of cancer and genetic diseases. These viruses can distinguish between healthy and diseased cells, selectively infecting the latter and delivering therapeutic payloads—such as anticancer agents or gene-editing tools.
This project will integrate machine learning to design more precise gene delivery vectors, optimizing their ability to target specific cells while minimizing off-target effects. These vectors will be validated in disease-relevant models to ensure safety and effectiveness.
Our goal is to develop next-generation virus-based therapies that are highly specific, adaptable, and effective across a range of human diseases.

Lead Supervisor

Professor Alan Parker

Lead Supervisor Email

ParkerAL@Cardiff.ac.uk

University Affiliation

Cardiff