Project Code
MRCIIAR26Ca Sewell
Project Type
Wet lab
Research Theme
Infection, Immunity, Antimicrobial Resistance and Repair
Project Summary Download
Summary
How do rare patients cure their own cancer?
Some individuals with advanced cancers achieve complete remission, defying the odds without standard treatment. This project will investigate the natural T-cells responsible for these outcomes. Working with unique samples from exceptional survivors, you will explore how these T-cells recognise and eliminate cancer, sometimes across multiple tumour types and unrelated individuals. Using advanced T-cell engineering and CRISPR screening, you will uncover new cancer-specific targets with genuine therapeutic potential. This is a rare opportunity to help decode natural immunity to cancer and contribute to the development of the next generation of immunotherapies.
Lead Supervisor
Professor Andrew Sewell
Lead Supervisor Email
University Affiliation
Cardiff